| Murrieta to Southern Pines (North Carolina) | 2,144.63 mi (3,451.45 km) |
| Murrieta to Southfield (Michigan) | 1,931.61 mi (3,108.62 km) |
| Murrieta to Southgate (Michigan) | 1,932.11 mi (3,109.43 km) |
| Murrieta to Southlake (Texas) | 1,156.79 mi (1,861.67 km) |
| Murrieta to Spanaway (Washington) | 973.75 mi (1,567.11 km) |
| Murrieta to Spanish Fork (Utah) | 545.86 mi (878.48 km) |
| Murrieta to Spanish Lake (Missouri) | 1,541.30 mi (2,480.49 km) |
| Murrieta to Spanish Springs (Nevada) | 442.27 mi (711.77 km) |
| Murrieta to Sparks (Nevada) | 437.66 mi (704.34 km) |
| Murrieta to Spartanburg (South Carolina) | 2,005.70 mi (3,227.87 km) |
| Murrieta to Spearfish (South Dakota) | 1,038.72 mi (1,671.66 km) |
| Murrieta to Speedway (Indiana) | 1,758.07 mi (2,829.34 km) |
| Murrieta to Spencer (Iowa) | 1,358.97 mi (2,187.05 km) |
| Murrieta to Spokane (Washington) | 973.97 mi (1,567.45 km) |
| Murrieta to Spokane Valley (Washington) | 973.58 mi (1,566.82 km) |
