| Murphy to Southern Pines (North Carolina) | 994.48 mi (1,600.47 km) |
| Murphy to Southfield (Michigan) | 977.09 mi (1,572.47 km) |
| Murphy to Southgate (Michigan) | 967.99 mi (1,557.84 km) |
| Murphy to Southlake (Texas) | 31.60 mi (50.85 km) |
| Murphy to Spanaway (Washington) | 1,663.48 mi (2,677.11 km) |
| Murphy to Spanish Fork (Utah) | 965.40 mi (1,553.66 km) |
| Murphy to Spanish Lake (Missouri) | 535.73 mi (862.17 km) |
| Murphy to Spanish Springs (Nevada) | 1,358.22 mi (2,185.84 km) |
| Murphy to Sparks (Nevada) | 1,359.41 mi (2,187.77 km) |
| Murphy to Spartanburg (South Carolina) | 851.03 mi (1,369.59 km) |
| Murphy to Spearfish (South Dakota) | 881.74 mi (1,419.02 km) |
| Murphy to Speedway (Indiana) | 741.51 mi (1,193.35 km) |
| Murphy to Spencer (Iowa) | 704.23 mi (1,133.35 km) |
| Murphy to Spokane (Washington) | 1,483.38 mi (2,387.27 km) |
| Murphy to Spokane Valley (Washington) | 1,475.69 mi (2,374.90 km) |
