| Mount Pleasant to Delaware (Ohio) | 544.17 mi (875.75 km) |
| Mount Pleasant to Delhi (California) | 2,317.24 mi (3,729.24 km) |
| Mount Pleasant to Delray Beach (Florida) | 442.40 mi (711.98 km) |
| Mount Pleasant to Deltona (Florida) | 285.06 mi (458.75 km) |
| Mount Pleasant to Deming (New Mexico) | 1,622.38 mi (2,610.97 km) |
| Mount Pleasant to Denison (Texas) | 968.77 mi (1,559.08 km) |
| Mount Pleasant to Dent (Ohio) | 514.48 mi (827.98 km) |
| Mount Pleasant to Denton (Texas) | 1,002.48 mi (1,613.34 km) |
| Mount Pleasant to Dentsville (South Carolina) | 106.77 mi (171.83 km) |
| Mount Pleasant to Denver (Colorado) | 1,468.62 mi (2,363.51 km) |
| Mount Pleasant to Depew (New York) | 697.59 mi (1,122.66 km) |
| Mount Pleasant to Derby (Connecticut) | 692.70 mi (1,114.80 km) |
| Mount Pleasant to Derby (Kansas) | 1,034.69 mi (1,665.17 km) |
| Mount Pleasant to Des Moines (Iowa) | 966.76 mi (1,555.86 km) |
| Mount Pleasant to Des Moines (Washington) | 2,422.06 mi (3,897.93 km) |
