| Mount Pleasant to Clarksdale (Mississippi) | 625.72 mi (1,007.00 km) |
| Mount Pleasant to Clarkston (Georgia) | 263.57 mi (424.18 km) |
| Mount Pleasant to Clarksville (Indiana) | 504.14 mi (811.34 km) |
| Mount Pleasant to Clarksville (Tennessee) | 498.13 mi (801.67 km) |
| Mount Pleasant to Clawson (Michigan) | 693.20 mi (1,115.60 km) |
| Mount Pleasant to Clay (Alabama) | 396.36 mi (637.88 km) |
| Mount Pleasant to Clayton (California) | 2,377.31 mi (3,825.92 km) |
| Mount Pleasant to Clayton (Missouri) | 711.56 mi (1,145.15 km) |
| Mount Pleasant to Clayton (North Carolina) | 209.03 mi (336.39 km) |
| Mount Pleasant to Clayton (Ohio) | 545.58 mi (878.03 km) |
| Mount Pleasant to Clearfield (Utah) | 1,854.46 mi (2,984.46 km) |
| Mount Pleasant to Clearlake (California) | 2,410.37 mi (3,879.11 km) |
| Mount Pleasant to Clearwater (Florida) | 379.64 mi (610.98 km) |
| Mount Pleasant to Cleburne (Texas) | 1,023.49 mi (1,647.14 km) |
| Mount Pleasant to Clemmons (North Carolina) | 221.94 mi (357.19 km) |
