| Mount Pleasant to Anoka (Minnesota) | 1,118.98 mi (1,800.83 km) |
| Mount Pleasant to Ansonia (Connecticut) | 694.14 mi (1,117.11 km) |
| Mount Pleasant to Antelope (California) | 2,342.98 mi (3,770.66 km) |
| Mount Pleasant to Anthem (Arizona) | 1,857.52 mi (2,989.40 km) |
| Mount Pleasant to Antioch (California) | 2,369.83 mi (3,813.87 km) |
| Mount Pleasant to Antioch (Illinois) | 802.54 mi (1,291.57 km) |
| Mount Pleasant to Apache Junction (Arizona) | 1,828.36 mi (2,942.45 km) |
| Mount Pleasant to Apex (North Carolina) | 205.52 mi (330.75 km) |
| Mount Pleasant to Apollo Beach (Florida) | 383.96 mi (617.93 km) |
| Mount Pleasant to Apopka (Florida) | 304.33 mi (489.77 km) |
| Mount Pleasant to Apple Valley (California) | 2,140.34 mi (3,444.55 km) |
| Mount Pleasant to Apple Valley (Minnesota) | 1,089.86 mi (1,753.96 km) |
| Mount Pleasant to Appleton (Wisconsin) | 913.86 mi (1,470.71 km) |
| Mount Pleasant to Arbutus (Maryland) | 474.68 mi (763.93 km) |
| Mount Pleasant to Arcadia (California) | 2,190.94 mi (3,525.97 km) |
