| Mount Pleasant to Altus (Oklahoma) | 1,124.51 mi (1,809.72 km) |
| Mount Pleasant to Alum Rock (California) | 2,374.91 mi (3,822.04 km) |
| Mount Pleasant to Alvin (Texas) | 945.07 mi (1,520.94 km) |
| Mount Pleasant to Amarillo (Texas) | 1,268.17 mi (2,040.93 km) |
| Mount Pleasant to Amelia (Ohio) | 492.33 mi (792.33 km) |
| Mount Pleasant to American Canyon (California) | 2,393.83 mi (3,852.50 km) |
| Mount Pleasant to American Fork (Utah) | 1,836.63 mi (2,955.77 km) |
| Mount Pleasant to Americus (Georgia) | 262.34 mi (422.20 km) |
| Mount Pleasant to Ames (Iowa) | 985.11 mi (1,585.39 km) |
| Mount Pleasant to Amherst (Ohio) | 605.31 mi (974.15 km) |
| Mount Pleasant to Ammon (Idaho) | 1,878.91 mi (3,023.82 km) |
| Mount Pleasant to Amsterdam (New York) | 761.15 mi (1,224.96 km) |
| Mount Pleasant to Anacortes (Washington) | 2,448.88 mi (3,941.10 km) |
| Mount Pleasant to Anaheim (California) | 2,183.88 mi (3,514.61 km) |
| Mount Pleasant to Anchorage (Alaska) | 3,578.48 mi (5,759.01 km) |
