| Most to San Luis Obispo (California) | 5,890.17 mi (9,479.31 km) |
| Most to San Marcos (California) | 5,926.35 mi (9,537.54 km) |
| Most to San Marcos (Texas) | 5,495.60 mi (8,844.31 km) |
| Most to San Marino (California) | 5,892.38 mi (9,482.86 km) |
| Most to San Mateo (California) | 5,790.41 mi (9,318.77 km) |
| Most to San Pablo (California) | 5,765.74 mi (9,279.06 km) |
| Most to San Rafael (California) | 5,768.37 mi (9,283.30 km) |
| Most to San Ramon (California) | 5,768.24 mi (9,283.09 km) |
| Most to San Tan Valley (Arizona) | 5,760.40 mi (9,270.47 km) |
| Most to Sand Springs (Oklahoma) | 5,089.42 mi (8,190.63 km) |
| Most to Sandusky (Ohio) | 4,334.42 mi (6,975.57 km) |
| Most to Sandy (Oregon) | 5,305.04 mi (8,537.64 km) |
| Most to Sandy (Utah) | 5,334.57 mi (8,585.17 km) |
| Most to Sandy Springs (Georgia) | 4,771.99 mi (7,679.78 km) |
| Most to Sanford (Florida) | 4,912.66 mi (7,906.16 km) |
