| Most to Medford (New York) | 3,993.96 mi (6,427.66 km) |
| Most to Medford (Oregon) | 5,507.06 mi (8,862.76 km) |
| Most to Medina (Ohio) | 4,318.69 mi (6,950.26 km) |
| Most to Medulla (Florida) | 4,984.32 mi (8,021.48 km) |
| Most to Mehlville (Missouri) | 4,758.91 mi (7,658.73 km) |
| Most to Melbourne (Florida) | 4,922.63 mi (7,922.20 km) |
| Most to Melissa (Texas) | 5,258.92 mi (8,463.41 km) |
| Most to Melrose (Massachusetts) | 3,844.95 mi (6,187.85 km) |
| Most to Melrose Park (Illinois) | 4,498.18 mi (7,239.12 km) |
| Most to Melville (New York) | 4,012.35 mi (6,457.25 km) |
| Most to Melvindale (Michigan) | 4,311.41 mi (6,938.54 km) |
| Most to Memphis (Florida) | 5,028.99 mi (8,093.37 km) |
| Most to Memphis (Tennessee) | 4,922.94 mi (7,922.71 km) |
| Most to Menasha (Wisconsin) | 4,402.38 mi (7,084.94 km) |
| Most to Mendota (California) | 5,791.29 mi (9,320.19 km) |
