| Most to Eggertsville (New York) | 4,117.66 mi (6,626.73 km) |
| Most to Egypt Lake-Leto (Florida) | 5,002.24 mi (8,050.33 km) |
| Most to El Cajon (California) | 5,940.52 mi (9,560.34 km) |
| Most to El Campo (Texas) | 5,472.13 mi (8,806.54 km) |
| Most to El Centro (California) | 5,901.62 mi (9,497.73 km) |
| Most to El Cerrito (California) | 5,767.45 mi (9,281.81 km) |
| Most to El Dorado (Arkansas) | 5,122.16 mi (8,243.31 km) |
| Most to El Dorado (Kansas) | 5,023.63 mi (8,084.76 km) |
| Most to El Dorado Hills (California) | 5,690.22 mi (9,157.52 km) |
| Most to El Mirage (Arizona) | 5,759.06 mi (9,268.32 km) |
| Most to El Monte (California) | 5,893.03 mi (9,483.92 km) |
| Most to El Paso (Texas) | 5,676.38 mi (9,135.25 km) |
| Most to El Paso de Robles (California) | 5,866.94 mi (9,441.93 km) |
| Most to El Reno (Oklahoma) | 5,185.20 mi (8,344.78 km) |
| Most to El Segundo (California) | 5,912.72 mi (9,515.60 km) |
