| Most to Eau Claire (Wisconsin) | 4,475.59 mi (7,202.77 km) |
| Most to Echelon (New Jersey) | 4,117.66 mi (6,626.73 km) |
| Most to Eden (North Carolina) | 4,463.56 mi (7,183.40 km) |
| Most to Eden Prairie (Minnesota) | 4,538.88 mi (7,304.63 km) |
| Most to Edgewater (Florida) | 4,890.33 mi (7,870.23 km) |
| Most to Edgewater (New Jersey) | 4,032.54 mi (6,489.75 km) |
| Most to Edgewood (Maryland) | 4,188.58 mi (6,740.88 km) |
| Most to Edgewood (Washington) | 5,192.68 mi (8,356.82 km) |
| Most to Edina (Minnesota) | 4,533.45 mi (7,295.88 km) |
| Most to Edinburg (Texas) | 5,700.49 mi (9,174.06 km) |
| Most to Edmond (Oklahoma) | 5,159.37 mi (8,303.20 km) |
| Most to Edmonds (Washington) | 5,158.52 mi (8,301.84 km) |
| Most to Edwards (Colorado) | 5,237.51 mi (8,428.96 km) |
| Most to Edwardsville (Illinois) | 4,732.17 mi (7,615.70 km) |
| Most to Effingham (Illinois) | 4,663.70 mi (7,505.50 km) |
