| Most to Sestao | 926.37 mi (1,490.86 km) |
| Most to Sevilla | 1,332.22 mi (2,143.99 km) |
| Most to Sevilla La Nueva | 1,102.43 mi (1,774.19 km) |
| Most to Silla | 1,028.37 mi (1,655.01 km) |
| Most to Silleda | 1,163.77 mi (1,872.91 km) |
| Most to Sitges | 854.79 mi (1,375.65 km) |
| Most to Socuellamos | 1,111.82 mi (1,789.31 km) |
| Most to Soller | 911.40 mi (1,466.76 km) |
| Most to Solsona | 823.18 mi (1,324.77 km) |
| Most to Son Servera | 901.95 mi (1,451.54 km) |
| Most to Sonseca | 1,131.86 mi (1,821.55 km) |
| Most to Sopelana | 922.32 mi (1,484.33 km) |
| Most to Soria | 975.65 mi (1,570.16 km) |
| Most to Suances | 962.89 mi (1,549.62 km) |
| Most to Sueca | 1,034.03 mi (1,664.11 km) |
