| Mobile to Southern Pines (North Carolina) | 593.38 mi (954.95 km) |
| Mobile to Southfield (Michigan) | 858.15 mi (1,381.05 km) |
| Mobile to Southgate (Michigan) | 841.47 mi (1,354.22 km) |
| Mobile to Southlake (Texas) | 553.01 mi (889.99 km) |
| Mobile to Spanaway (Washington) | 2,140.40 mi (3,444.65 km) |
| Mobile to Spanish Fork (Utah) | 1,470.34 mi (2,366.29 km) |
| Mobile to Spanish Lake (Missouri) | 572.76 mi (921.76 km) |
| Mobile to Spanish Springs (Nevada) | 1,875.55 mi (3,018.41 km) |
| Mobile to Sparks (Nevada) | 1,877.07 mi (3,020.85 km) |
| Mobile to Spartanburg (South Carolina) | 464.72 mi (747.89 km) |
| Mobile to Spearfish (South Dakota) | 1,279.84 mi (2,059.71 km) |
| Mobile to Speedway (Indiana) | 638.54 mi (1,027.62 km) |
| Mobile to Spencer (Iowa) | 944.26 mi (1,519.64 km) |
| Mobile to Spokane (Washington) | 1,941.05 mi (3,123.83 km) |
| Mobile to Spokane Valley (Washington) | 1,932.67 mi (3,110.33 km) |
