| Missouri City to Olympia Heights (Florida) | 966.40 mi (1,555.28 km) |
| Missouri City to Omaha (Nebraska) | 808.89 mi (1,301.78 km) |
| Missouri City to On Top of the World Designated Place (Florida) | 798.28 mi (1,284.72 km) |
| Missouri City to Onalaska (Wisconsin) | 1,018.00 mi (1,638.32 km) |
| Missouri City to Oneida (New York) | 1,441.07 mi (2,319.18 km) |
| Missouri City to Oneonta (New York) | 1,443.33 mi (2,322.82 km) |
| Missouri City to Ontario (California) | 1,329.48 mi (2,139.60 km) |
| Missouri City to Ontario (Oregon) | 1,542.62 mi (2,482.61 km) |
| Missouri City to Opa-locka (Florida) | 967.37 mi (1,556.84 km) |
| Missouri City to Opelika (Alabama) | 637.63 mi (1,026.17 km) |
| Missouri City to Opelousas (Louisiana) | 217.06 mi (349.32 km) |
| Missouri City to Orange (California) | 1,339.77 mi (2,156.15 km) |
| Missouri City to Orange (Texas) | 113.23 mi (182.23 km) |
| Missouri City to Orange City (Florida) | 859.51 mi (1,383.25 km) |
| Missouri City to Orangeburg (South Carolina) | 904.64 mi (1,455.88 km) |
