| Milpitas to Southern Pines (North Carolina) | 2,350.57 mi (3,782.88 km) |
| Milpitas to Southfield (Michigan) | 2,057.33 mi (3,310.95 km) |
| Milpitas to Southgate (Michigan) | 2,061.32 mi (3,317.37 km) |
| Milpitas to Southlake (Texas) | 1,426.44 mi (2,295.64 km) |
| Milpitas to Spanaway (Washington) | 668.29 mi (1,075.50 km) |
| Milpitas to Spanish Fork (Utah) | 581.96 mi (936.58 km) |
| Milpitas to Spanish Lake (Missouri) | 1,716.41 mi (2,762.30 km) |
| Milpitas to Spanish Springs (Nevada) | 194.98 mi (313.79 km) |
| Milpitas to Sparks (Nevada) | 188.95 mi (304.08 km) |
| Milpitas to Spartanburg (South Carolina) | 2,218.68 mi (3,570.63 km) |
| Milpitas to Spearfish (South Dakota) | 1,058.51 mi (1,703.51 km) |
| Milpitas to Speedway (Indiana) | 1,918.52 mi (3,087.57 km) |
| Milpitas to Spencer (Iowa) | 1,456.46 mi (2,343.94 km) |
| Milpitas to Spokane (Washington) | 742.27 mi (1,194.56 km) |
| Milpitas to Spokane Valley (Washington) | 745.09 mi (1,199.11 km) |
