| Middlewich to Spello | 987.91 mi (1,589.88 km) |
| Middlewich to Spilamberto | 853.06 mi (1,372.87 km) |
| Middlewich to Spilimbergo | 838.74 mi (1,349.83 km) |
| Middlewich to Spinea | 842.91 mi (1,356.54 km) |
| Middlewich to Spoleto | 1,000.81 mi (1,610.65 km) |
| Middlewich to Spoltore | 1,063.86 mi (1,712.12 km) |
| Middlewich to Spresiano | 832.15 mi (1,339.21 km) |
| Middlewich to Squinzano | 1,301.42 mi (2,094.43 km) |
| Middlewich to Statte | 1,265.56 mi (2,036.72 km) |
| Middlewich to Stezzano | 751.15 mi (1,208.86 km) |
| Middlewich to Strada | 913.13 mi (1,469.53 km) |
| Middlewich to Stradella | 769.90 mi (1,239.03 km) |
| Middlewich to Striano | 1,166.10 mi (1,876.65 km) |
| Middlewich to Subiaco | 1,058.65 mi (1,703.73 km) |
| Middlewich to Sulmona | 1,078.62 mi (1,735.88 km) |
