| Middlewich to Sacile | 832.38 mi (1,339.58 km) |
| Middlewich to Sala Consilina | 1,221.89 mi (1,966.44 km) |
| Middlewich to Salemi | 1,287.74 mi (2,072.41 km) |
| Middlewich to Salerno | 1,179.69 mi (1,898.53 km) |
| Middlewich to Salo | 782.48 mi (1,259.28 km) |
| Middlewich to Salsomaggiore Terme | 805.32 mi (1,296.05 km) |
| Middlewich to Saluzzo | 741.60 mi (1,193.49 km) |
| Middlewich to Salzano | 839.45 mi (1,350.97 km) |
| Middlewich to Samarate | 725.50 mi (1,167.58 km) |
| Middlewich to San Benedetto del Tronto | 1,029.40 mi (1,656.65 km) |
| Middlewich to San Biagio di Callalta | 841.34 mi (1,354.01 km) |
| Middlewich to San Bonifacio | 817.53 mi (1,315.69 km) |
| Middlewich to San Casciano in Val di Pesa | 905.07 mi (1,456.57 km) |
| Middlewich to San Cataldo | 1,340.14 mi (2,156.74 km) |
| Middlewich to San Cesareo | 1,055.78 mi (1,699.11 km) |
