| Middletown to University Place (Washington) | 1,969.01 mi (3,168.81 km) |
| Middletown to Upland (California) | 1,867.88 mi (3,006.07 km) |
| Middletown to Upper Arlington (Ohio) | 77.74 mi (125.12 km) |
| Middletown to Upper Grand Lagoon (Florida) | 649.61 mi (1,045.44 km) |
| Middletown to Upper Montclair (New Jersey) | 544.27 mi (875.91 km) |
| Middletown to Urbana (Illinois) | 207.63 mi (334.15 km) |
| Middletown to Urbana (Maryland) | 375.01 mi (603.53 km) |
| Middletown to Urbana (Ohio) | 52.94 mi (85.20 km) |
| Middletown to Urbandale (Iowa) | 515.39 mi (829.45 km) |
| Middletown to Utica (New York) | 535.02 mi (861.04 km) |
| Middletown to Uvalde (Texas) | 1,127.64 mi (1,814.77 km) |
| Middletown to Vacaville (California) | 2,007.79 mi (3,231.22 km) |
| Middletown to Vadnais Heights (Minnesota) | 587.14 mi (944.91 km) |
| Middletown to Vail (Arizona) | 1,557.19 mi (2,506.06 km) |
| Middletown to Valdosta (Georgia) | 601.00 mi (967.22 km) |
