| Middletown to Stephenville (Texas) | 923.26 mi (1,485.84 km) |
| Middletown to Sterling (Colorado) | 996.64 mi (1,603.94 km) |
| Middletown to Sterling (Illinois) | 321.20 mi (516.92 km) |
| Middletown to Sterling (Virginia) | 373.91 mi (601.76 km) |
| Middletown to Sterling Heights (Michigan) | 223.73 mi (360.06 km) |
| Middletown to Steubenville (Ohio) | 205.56 mi (330.82 km) |
| Middletown to Stevens Point (Wisconsin) | 437.04 mi (703.35 km) |
| Middletown to Stevenson Ranch (California) | 1,910.62 mi (3,074.84 km) |
| Middletown to Stillwater (Minnesota) | 577.81 mi (929.90 km) |
| Middletown to Stillwater (Oklahoma) | 730.94 mi (1,176.33 km) |
| Middletown to Stockbridge (Georgia) | 413.10 mi (664.82 km) |
| Middletown to Stockton (California) | 1,979.87 mi (3,186.29 km) |
| Middletown to Stone Ridge (Virginia) | 366.62 mi (590.01 km) |
| Middletown to Stonecrest (Georgia) | 402.26 mi (647.38 km) |
| Middletown to Stony Brook (New York) | 600.46 mi (966.35 km) |
