| Middletown to Security-Widefield (Colorado) | 1,089.59 mi (1,753.52 km) |
| Middletown to Sedalia (Missouri) | 478.46 mi (770.00 km) |
| Middletown to Sedro-Woolley (Washington) | 1,958.98 mi (3,152.68 km) |
| Middletown to Seguin (Texas) | 1,031.45 mi (1,659.95 km) |
| Middletown to Selden (New York) | 604.45 mi (972.77 km) |
| Middletown to Selma (Alabama) | 511.80 mi (823.66 km) |
| Middletown to Selma (California) | 1,916.56 mi (3,084.41 km) |
| Middletown to Selma (Texas) | 1,046.27 mi (1,683.82 km) |
| Middletown to Seminole (Florida) | 810.69 mi (1,304.68 km) |
| Middletown to Seven Hills (Ohio) | 191.98 mi (308.96 km) |
| Middletown to Seven Oaks (South Carolina) | 416.94 mi (670.99 km) |
| Middletown to Severn (Maryland) | 410.66 mi (660.89 km) |
| Middletown to Severna Park (Maryland) | 417.78 mi (672.36 km) |
| Middletown to Sevierville (Tennessee) | 253.63 mi (408.17 km) |
| Middletown to Seymour (Indiana) | 90.21 mi (145.18 km) |
