| Middletown to Effingham (Illinois) | 225.26 mi (362.52 km) |
| Middletown to Eggertsville (New York) | 374.95 mi (603.42 km) |
| Middletown to Egypt Lake-Leto (Florida) | 800.68 mi (1,288.57 km) |
| Middletown to El Cajon (California) | 1,865.38 mi (3,002.04 km) |
| Middletown to El Campo (Texas) | 982.11 mi (1,580.55 km) |
| Middletown to El Centro (California) | 1,791.37 mi (2,882.93 km) |
| Middletown to El Cerrito (California) | 2,033.09 mi (3,271.94 km) |
| Middletown to El Dorado (Arkansas) | 633.29 mi (1,019.18 km) |
| Middletown to El Dorado (Kansas) | 683.50 mi (1,099.99 km) |
| Middletown to El Dorado Hills (California) | 1,954.36 mi (3,145.23 km) |
| Middletown to El Mirage (Arizona) | 1,597.79 mi (2,571.40 km) |
| Middletown to El Monte (California) | 1,888.64 mi (3,039.47 km) |
| Middletown to El Paso (Texas) | 1,342.04 mi (2,159.81 km) |
| Middletown to El Paso de Robles (California) | 1,991.63 mi (3,205.22 km) |
| Middletown to El Reno (Oklahoma) | 792.91 mi (1,276.07 km) |
