| Middletown to Eatontown (New Jersey) | 548.91 mi (883.38 km) |
| Middletown to Eau Claire (Wisconsin) | 517.52 mi (832.87 km) |
| Middletown to Echelon (New Jersey) | 498.64 mi (802.48 km) |
| Middletown to Eden (North Carolina) | 326.08 mi (524.77 km) |
| Middletown to Eden Prairie (Minnesota) | 593.69 mi (955.46 km) |
| Middletown to Edgewater (Florida) | 754.16 mi (1,213.70 km) |
| Middletown to Edgewater (New Jersey) | 555.89 mi (894.63 km) |
| Middletown to Edgewood (Maryland) | 430.35 mi (692.59 km) |
| Middletown to Edgewood (Washington) | 1,956.71 mi (3,149.02 km) |
| Middletown to Edina (Minnesota) | 591.45 mi (951.85 km) |
| Middletown to Edinburg (Texas) | 1,209.38 mi (1,946.31 km) |
| Middletown to Edmond (Oklahoma) | 761.17 mi (1,224.98 km) |
| Middletown to Edmonds (Washington) | 1,961.59 mi (3,156.88 km) |
| Middletown to Edwards (Colorado) | 1,182.29 mi (1,902.71 km) |
| Middletown to Edwardsville (Illinois) | 305.15 mi (491.08 km) |
