| Middleton to Emeryville (California) | 5,184.80 mi (8,344.13 km) |
| Middleton to Emmaus (Pennsylvania) | 3,404.38 mi (5,478.82 km) |
| Middleton to Emporia (Kansas) | 4,294.08 mi (6,910.65 km) |
| Middleton to Encinitas (California) | 5,309.08 mi (8,544.14 km) |
| Middleton to Endicott (New York) | 3,355.91 mi (5,400.81 km) |
| Middleton to Endwell (New York) | 3,353.36 mi (5,396.70 km) |
| Middleton to Englewood (Colorado) | 4,537.88 mi (7,303.01 km) |
| Middleton to Englewood (Florida) | 4,347.15 mi (6,996.07 km) |
| Middleton to Englewood (New Jersey) | 3,328.01 mi (5,355.91 km) |
| Middleton to Englewood (Ohio) | 3,778.09 mi (6,080.25 km) |
| Middleton to Enid (Oklahoma) | 4,458.37 mi (7,175.05 km) |
| Middleton to Ennis (Texas) | 4,627.15 mi (7,446.67 km) |
| Middleton to Ensley (Florida) | 4,359.84 mi (7,016.49 km) |
| Middleton to Enterprise (Alabama) | 4,262.16 mi (6,859.28 km) |
| Middleton to Enterprise (Nevada) | 5,074.88 mi (8,167.24 km) |
