| Middlesex to St. Simons (Georgia) | 754.44 mi (1,214.16 km) |
| Middlesex to Stafford (Texas) | 1,404.95 mi (2,261.05 km) |
| Middlesex to Stallings (North Carolina) | 505.22 mi (813.08 km) |
| Middlesex to Stamford (Connecticut) | 61.37 mi (98.76 km) |
| Middlesex to Stanford (California) | 2,537.47 mi (4,083.66 km) |
| Middlesex to Stanton (California) | 2,414.22 mi (3,885.31 km) |
| Middlesex to Star (Idaho) | 2,139.11 mi (3,442.56 km) |
| Middlesex to Starkville (Mississippi) | 929.01 mi (1,495.10 km) |
| Middlesex to State College (Pennsylvania) | 176.44 mi (283.96 km) |
| Middlesex to Staten Island (New York) | 18.46 mi (29.70 km) |
| Middlesex to Statesboro (Georgia) | 691.71 mi (1,113.20 km) |
| Middlesex to Statesville (North Carolina) | 478.54 mi (770.14 km) |
| Middlesex to Staunton (Virginia) | 295.19 mi (475.06 km) |
| Middlesex to Steamboat Springs (Colorado) | 1,687.91 mi (2,716.44 km) |
| Middlesex to Steiner Ranch (Texas) | 1,486.88 mi (2,392.90 km) |
