| Middlesex to St. George (Utah) | 2,099.83 mi (3,379.35 km) |
| Middlesex to St. Helens (Oregon) | 2,422.38 mi (3,898.45 km) |
| Middlesex to St. James (New York) | 73.65 mi (118.52 km) |
| Middlesex to St. John (Indiana) | 678.18 mi (1,091.42 km) |
| Middlesex to St. Joseph (Missouri) | 1,071.96 mi (1,725.16 km) |
| Middlesex to St. Louis (Missouri) | 847.56 mi (1,364.01 km) |
| Middlesex to St. Louis Park (Minnesota) | 1,000.80 mi (1,610.64 km) |
| Middlesex to St. Marys (Georgia) | 785.27 mi (1,263.76 km) |
| Middlesex to St. Marys (Pennsylvania) | 218.90 mi (352.29 km) |
| Middlesex to St. Matthews (Kentucky) | 615.36 mi (990.32 km) |
| Middlesex to St. Michael (Minnesota) | 1,019.85 mi (1,641.30 km) |
| Middlesex to St. Paul (Minnesota) | 988.27 mi (1,590.46 km) |
| Middlesex to St. Peter (Minnesota) | 1,022.95 mi (1,646.28 km) |
| Middlesex to St. Peters (Missouri) | 864.07 mi (1,390.59 km) |
| Middlesex to St. Petersburg (Florida) | 997.67 mi (1,605.59 km) |
