| Middlesex to Shelton (Connecticut) | 87.26 mi (140.43 km) |
| Middlesex to Shelton (Washington) | 2,422.89 mi (3,899.27 km) |
| Middlesex to Shenandoah (Louisiana) | 1,161.04 mi (1,868.51 km) |
| Middlesex to Shepherdsville (Kentucky) | 624.71 mi (1,005.37 km) |
| Middlesex to Sheridan (Wyoming) | 1,662.95 mi (2,676.25 km) |
| Middlesex to Sherman (Texas) | 1,305.64 mi (2,101.22 km) |
| Middlesex to Sherrelwood (Colorado) | 1,602.17 mi (2,578.44 km) |
| Middlesex to Sherwood (Arkansas) | 1,042.88 mi (1,678.35 km) |
| Middlesex to Sherwood (Oregon) | 2,429.27 mi (3,909.53 km) |
| Middlesex to Shiloh (Illinois) | 831.75 mi (1,338.57 km) |
| Middlesex to Shiloh (Ohio) | 515.95 mi (830.34 km) |
| Middlesex to Shiloh (Pennsylvania) | 127.71 mi (205.52 km) |
| Middlesex to Shirley (New York) | 86.54 mi (139.28 km) |
| Middlesex to Shively (Kentucky) | 625.53 mi (1,006.70 km) |
| Middlesex to Shoreline (Washington) | 2,382.88 mi (3,834.87 km) |
