| Middlesex to Security-Widefield (Colorado) | 1,604.09 mi (2,581.53 km) |
| Middlesex to Sedalia (Missouri) | 1,003.10 mi (1,614.33 km) |
| Middlesex to Sedro-Woolley (Washington) | 2,372.82 mi (3,818.68 km) |
| Middlesex to Seguin (Texas) | 1,521.49 mi (2,448.60 km) |
| Middlesex to Selden (New York) | 78.88 mi (126.94 km) |
| Middlesex to Selma (Alabama) | 894.10 mi (1,438.92 km) |
| Middlesex to Selma (California) | 2,425.94 mi (3,904.18 km) |
| Middlesex to Selma (Texas) | 1,538.37 mi (2,475.77 km) |
| Middlesex to Seminole (Florida) | 997.70 mi (1,605.64 km) |
| Middlesex to Seven Hills (Ohio) | 378.15 mi (608.57 km) |
| Middlesex to Seven Oaks (South Carolina) | 579.80 mi (933.09 km) |
| Middlesex to Severn (Maryland) | 153.07 mi (246.34 km) |
| Middlesex to Severna Park (Maryland) | 150.31 mi (241.91 km) |
| Middlesex to Sevierville (Tennessee) | 588.60 mi (947.27 km) |
| Middlesex to Seymour (Indiana) | 614.85 mi (989.51 km) |
