| Middlesex to Saddlebrooke (Arizona) | 2,076.95 mi (3,342.53 km) |
| Middlesex to Safety Harbor (Florida) | 985.14 mi (1,585.42 km) |
| Middlesex to Saginaw (Michigan) | 523.13 mi (841.89 km) |
| Middlesex to Saginaw (Texas) | 1,368.59 mi (2,202.53 km) |
| Middlesex to Sahuarita (Arizona) | 2,100.96 mi (3,381.16 km) |
| Middlesex to Saks (Alabama) | 783.60 mi (1,261.08 km) |
| Middlesex to Salem (Massachusetts) | 229.26 mi (368.96 km) |
| Middlesex to Salem (Ohio) | 333.04 mi (535.97 km) |
| Middlesex to Salem (Oregon) | 2,443.29 mi (3,932.09 km) |
| Middlesex to Salem (Virginia) | 375.02 mi (603.53 km) |
| Middlesex to Salem Lakes (Wisconsin) | 716.78 mi (1,153.55 km) |
| Middlesex to Salida (California) | 2,475.03 mi (3,983.17 km) |
| Middlesex to Salina (Kansas) | 1,231.26 mi (1,981.52 km) |
| Middlesex to Salinas (California) | 2,527.65 mi (4,067.87 km) |
| Middlesex to Salisbury (Maryland) | 162.57 mi (261.64 km) |
