| Middlesex to Lovington (New Mexico) | 1,672.66 mi (2,691.89 km) |
| Middlesex to Lowell (Indiana) | 675.51 mi (1,087.13 km) |
| Middlesex to Lowell (Massachusetts) | 217.52 mi (350.06 km) |
| Middlesex to Lower Burrell (Pennsylvania) | 273.53 mi (440.20 km) |
| Middlesex to Lowes Island (Virginia) | 184.48 mi (296.88 km) |
| Middlesex to Lubbock (Texas) | 1,578.09 mi (2,539.69 km) |
| Middlesex to Lufkin (Texas) | 1,294.95 mi (2,084.02 km) |
| Middlesex to Luling (Louisiana) | 1,156.10 mi (1,860.56 km) |
| Middlesex to Lumberton (North Carolina) | 479.17 mi (771.16 km) |
| Middlesex to Lumberton (Texas) | 1,314.16 mi (2,114.93 km) |
| Middlesex to Lutz (Florida) | 970.31 mi (1,561.57 km) |
| Middlesex to Lynbrook (New York) | 43.75 mi (70.41 km) |
| Middlesex to Lynchburg (Virginia) | 333.87 mi (537.32 km) |
| Middlesex to Lynden (Washington) | 2,380.46 mi (3,830.98 km) |
| Middlesex to Lyndhurst (Ohio) | 369.97 mi (595.41 km) |
