| Middlesex to Indianapolis (Indiana) | 616.76 mi (992.57 km) |
| Middlesex to Indianola (Iowa) | 994.06 mi (1,599.79 km) |
| Middlesex to Indio (California) | 2,323.85 mi (3,739.88 km) |
| Middlesex to Inglewood (California) | 2,428.21 mi (3,907.82 km) |
| Middlesex to Inkster (Michigan) | 471.51 mi (758.82 km) |
| Middlesex to Inver Grove Heights (Minnesota) | 984.51 mi (1,584.41 km) |
| Middlesex to Inwood (New York) | 39.51 mi (63.58 km) |
| Middlesex to Iona (Florida) | 1,061.02 mi (1,707.55 km) |
| Middlesex to Ionia (Michigan) | 569.00 mi (915.72 km) |
| Middlesex to Iowa City (Iowa) | 888.13 mi (1,429.31 km) |
| Middlesex to Irmo (South Carolina) | 578.61 mi (931.19 km) |
| Middlesex to Irondale (Alabama) | 826.63 mi (1,330.33 km) |
| Middlesex to Ironton (Ohio) | 457.68 mi (736.56 km) |
| Middlesex to Irvine (California) | 2,406.19 mi (3,872.39 km) |
| Middlesex to Irving (Texas) | 1,348.89 mi (2,170.83 km) |
