| Middlesex to El Segundo (California) | 2,432.33 mi (3,914.45 km) |
| Middlesex to El Sobrante (California) | 2,384.35 mi (3,837.25 km) |
| Middlesex to Eldersburg (Maryland) | 152.90 mi (246.08 km) |
| Middlesex to Elfers (Florida) | 973.09 mi (1,566.04 km) |
| Middlesex to Elgin (Illinois) | 723.72 mi (1,164.71 km) |
| Middlesex to Elizabeth (New Jersey) | 17.43 mi (28.05 km) |
| Middlesex to Elizabeth City (North Carolina) | 310.26 mi (499.32 km) |
| Middlesex to Elizabethton (Tennessee) | 510.48 mi (821.54 km) |
| Middlesex to Elizabethtown (Kentucky) | 640.56 mi (1,030.88 km) |
| Middlesex to Elizabethtown (Pennsylvania) | 114.21 mi (183.80 km) |
| Middlesex to Elk City (Oklahoma) | 1,398.94 mi (2,251.38 km) |
| Middlesex to Elk Grove (California) | 2,474.48 mi (3,982.29 km) |
| Middlesex to Elk Grove Village (Illinois) | 706.58 mi (1,137.13 km) |
| Middlesex to Elk Plain (Washington) | 2,389.64 mi (3,845.75 km) |
| Middlesex to Elk River (Minnesota) | 1,015.74 mi (1,634.68 km) |
