| Middlesex to Effingham (Illinois) | 751.21 mi (1,208.96 km) |
| Middlesex to Eggertsville (New York) | 276.60 mi (445.14 km) |
| Middlesex to Egypt Lake-Leto (Florida) | 979.48 mi (1,576.32 km) |
| Middlesex to El Cajon (California) | 2,388.91 mi (3,844.57 km) |
| Middlesex to El Campo (Texas) | 1,456.63 mi (2,344.21 km) |
| Middlesex to El Centro (California) | 2,315.84 mi (3,726.98 km) |
| Middlesex to El Cerrito (California) | 2,532.84 mi (4,076.21 km) |
| Middlesex to El Dorado (Arkansas) | 1,121.94 mi (1,805.58 km) |
| Middlesex to El Dorado (Kansas) | 1,208.94 mi (1,945.60 km) |
| Middlesex to El Dorado Hills (California) | 2,451.64 mi (3,945.53 km) |
| Middlesex to El Mirage (Arizona) | 2,122.89 mi (3,416.45 km) |
| Middlesex to El Monte (California) | 2,408.42 mi (3,875.97 km) |
| Middlesex to El Paso (Texas) | 1,867.27 mi (3,005.08 km) |
| Middlesex to El Paso de Robles (California) | 2,503.56 mi (4,029.09 km) |
| Middlesex to El Reno (Oklahoma) | 1,318.61 mi (2,122.10 km) |
