| Middlesex to Des Plaines (Illinois) | 702.03 mi (1,129.80 km) |
| Middlesex to Desert Hot Springs (California) | 2,333.84 mi (3,755.95 km) |
| Middlesex to DeSoto (Texas) | 1,352.48 mi (2,176.60 km) |
| Middlesex to Destin (Florida) | 971.88 mi (1,564.08 km) |
| Middlesex to Destrehan (Louisiana) | 1,153.80 mi (1,856.86 km) |
| Middlesex to Detroit (Michigan) | 462.22 mi (743.87 km) |
| Middlesex to Diamond Bar (California) | 2,399.34 mi (3,861.36 km) |
| Middlesex to Diamond Springs (California) | 2,440.52 mi (3,927.63 km) |
| Middlesex to Dickinson (North Dakota) | 1,469.15 mi (2,364.36 km) |
| Middlesex to Dickinson (Texas) | 1,388.61 mi (2,234.75 km) |
| Middlesex to Dickson (Tennessee) | 762.89 mi (1,227.76 km) |
| Middlesex to Difficult Run (Virginia) | 190.31 mi (306.27 km) |
| Middlesex to Dinuba (California) | 2,415.39 mi (3,887.19 km) |
| Middlesex to Discovery Bay (California) | 2,496.98 mi (4,018.50 km) |
| Middlesex to Dix Hills (New York) | 62.98 mi (101.36 km) |
