| Middlesbrough to Shotley Bridge | 32.12 mi (51.69 km) |
| Middlesbrough to Shrewsbury | 143.31 mi (230.63 km) |
| Middlesbrough to Sidcup | 224.66 mi (361.55 km) |
| Middlesbrough to Sidmouth | 282.01 mi (453.85 km) |
| Middlesbrough to Sileby | 127.64 mi (205.41 km) |
| Middlesbrough to Sittingbourne | 238.25 mi (383.42 km) |
| Middlesbrough to Skegness | 118.06 mi (190.01 km) |
| Middlesbrough to Skelmersdale | 94.52 mi (152.11 km) |
| Middlesbrough to Skipton | 52.85 mi (85.06 km) |
| Middlesbrough to Sleaford | 114.26 mi (183.88 km) |
| Middlesbrough to Slough | 213.70 mi (343.91 km) |
| Middlesbrough to Small Heath | 148.24 mi (238.57 km) |
| Middlesbrough to Smethwick | 147.07 mi (236.69 km) |
| Middlesbrough to Snaresbrook | 212.97 mi (342.75 km) |
| Middlesbrough to Snodland | 235.11 mi (378.38 km) |
