| Middlesbrough to Eckington | 87.81 mi (141.32 km) |
| Middlesbrough to Edgware | 208.25 mi (335.15 km) |
| Middlesbrough to Edinburgh | 122.31 mi (196.84 km) |
| Middlesbrough to Edmonton | 210.23 mi (338.33 km) |
| Middlesbrough to Egg Buckland | 312.85 mi (503.49 km) |
| Middlesbrough to Elgin | 226.93 mi (365.20 km) |
| Middlesbrough to Elland | 66.42 mi (106.89 km) |
| Middlesbrough to Ellesmere Port | 112.28 mi (180.70 km) |
| Middlesbrough to Ellon | 195.50 mi (314.63 km) |
| Middlesbrough to Eltham | 222.49 mi (358.06 km) |
| Middlesbrough to Ely | 162.62 mi (261.72 km) |
| Middlesbrough to Emsworth | 257.86 mi (414.98 km) |
| Middlesbrough to Enfield | 207.65 mi (334.18 km) |
| Middlesbrough to Enfield Lock | 207.09 mi (333.27 km) |
| Middlesbrough to Englefield Green | 219.16 mi (352.70 km) |
