| Middlesbrough to Sesena | 1,006.46 mi (1,619.74 km) |
| Middlesbrough to Sestao | 782.47 mi (1,259.26 km) |
| Middlesbrough to Sevilla | 1,218.77 mi (1,961.42 km) |
| Middlesbrough to Sevilla La Nueva | 991.56 mi (1,595.76 km) |
| Middlesbrough to Silla | 1,051.95 mi (1,692.95 km) |
| Middlesbrough to Silleda | 879.55 mi (1,415.50 km) |
| Middlesbrough to Sitges | 932.36 mi (1,500.49 km) |
| Middlesbrough to Socuellamos | 1,058.47 mi (1,703.44 km) |
| Middlesbrough to Soller | 1,039.42 mi (1,672.78 km) |
| Middlesbrough to Solsona | 878.34 mi (1,413.56 km) |
| Middlesbrough to Son Servera | 1,055.15 mi (1,698.09 km) |
| Middlesbrough to Sonseca | 1,035.57 mi (1,666.59 km) |
| Middlesbrough to Sopelana | 777.49 mi (1,251.25 km) |
| Middlesbrough to Soria | 886.87 mi (1,427.27 km) |
| Middlesbrough to Suances | 780.27 mi (1,255.72 km) |
