| Middle Valley to Southern Pines (North Carolina) | 327.01 mi (526.26 km) |
| Middle Valley to Southfield (Michigan) | 514.23 mi (827.57 km) |
| Middle Valley to Southgate (Michigan) | 496.52 mi (799.07 km) |
| Middle Valley to Southlake (Texas) | 700.89 mi (1,127.97 km) |
| Middle Valley to Spanaway (Washington) | 2,080.04 mi (3,347.49 km) |
| Middle Valley to Spanish Fork (Utah) | 1,480.18 mi (2,382.12 km) |
| Middle Valley to Spanish Lake (Missouri) | 371.91 mi (598.52 km) |
| Middle Valley to Spanish Springs (Nevada) | 1,904.74 mi (3,065.39 km) |
| Middle Valley to Sparks (Nevada) | 1,907.41 mi (3,069.68 km) |
| Middle Valley to Spartanburg (South Carolina) | 185.73 mi (298.90 km) |
| Middle Valley to Spearfish (South Dakota) | 1,174.22 mi (1,889.73 km) |
| Middle Valley to Speedway (Indiana) | 323.42 mi (520.50 km) |
| Middle Valley to Spencer (Iowa) | 765.04 mi (1,231.21 km) |
| Middle Valley to Spokane (Washington) | 1,860.93 mi (2,994.88 km) |
| Middle Valley to Spokane Valley (Washington) | 1,851.97 mi (2,980.46 km) |
