| Middle Valley to Shoreham-by-Sea | 4,179.97 mi (6,727.02 km) |
| Middle Valley to Shotley Bridge | 4,026.30 mi (6,479.71 km) |
| Middle Valley to Shrewsbury | 4,036.96 mi (6,496.85 km) |
| Middle Valley to Sidcup | 4,180.75 mi (6,728.26 km) |
| Middle Valley to Sidmouth | 4,061.60 mi (6,536.51 km) |
| Middle Valley to Sileby | 4,101.83 mi (6,601.25 km) |
| Middle Valley to Sittingbourne | 4,208.56 mi (6,773.02 km) |
| Middle Valley to Skegness | 4,149.17 mi (6,677.45 km) |
| Middle Valley to Skelmersdale | 4,018.33 mi (6,466.88 km) |
| Middle Valley to Skipton | 4,039.26 mi (6,500.56 km) |
| Middle Valley to Sleaford | 4,123.06 mi (6,635.42 km) |
| Middle Valley to Slough | 4,150.91 mi (6,680.25 km) |
| Middle Valley to Small Heath | 4,078.14 mi (6,563.14 km) |
| Middle Valley to Smethwick | 4,072.91 mi (6,554.72 km) |
| Middle Valley to Snaresbrook | 4,173.31 mi (6,716.29 km) |
