| Middle River to University Place (Washington) | 2,346.72 mi (3,776.69 km) |
| Middle River to Upland (California) | 2,291.70 mi (3,688.14 km) |
| Middle River to Upper Arlington (Ohio) | 356.39 mi (573.55 km) |
| Middle River to Upper Grand Lagoon (Florida) | 824.50 mi (1,326.90 km) |
| Middle River to Upper Montclair (New Jersey) | 156.72 mi (252.22 km) |
| Middle River to Urbana (Illinois) | 627.34 mi (1,009.60 km) |
| Middle River to Urbana (Maryland) | 49.02 mi (78.89 km) |
| Middle River to Urbana (Ohio) | 392.91 mi (632.32 km) |
| Middle River to Urbandale (Iowa) | 924.02 mi (1,487.07 km) |
| Middle River to Utica (New York) | 266.66 mi (429.14 km) |
| Middle River to Uvalde (Texas) | 1,499.44 mi (2,413.11 km) |
| Middle River to Vacaville (California) | 2,425.10 mi (3,902.83 km) |
| Middle River to Vadnais Heights (Minnesota) | 936.84 mi (1,507.70 km) |
| Middle River to Vail (Arizona) | 1,975.73 mi (3,179.63 km) |
| Middle River to Valdosta (Georgia) | 702.67 mi (1,130.83 km) |
