| Middle River to Seymour (Tennessee) | 467.52 mi (752.41 km) |
| Middle River to Shady Hills (Florida) | 832.88 mi (1,340.39 km) |
| Middle River to Shafter (California) | 2,340.80 mi (3,767.15 km) |
| Middle River to Shaker Heights (Ohio) | 307.09 mi (494.22 km) |
| Middle River to Shakopee (Minnesota) | 949.45 mi (1,527.99 km) |
| Middle River to Sharon (Pennsylvania) | 251.30 mi (404.43 km) |
| Middle River to Sharonville (Ohio) | 426.57 mi (686.49 km) |
| Middle River to Shasta Lake (California) | 2,405.49 mi (3,871.26 km) |
| Middle River to Shawnee (Kansas) | 983.10 mi (1,582.14 km) |
| Middle River to Shawnee (Oklahoma) | 1,158.58 mi (1,864.55 km) |
| Middle River to Sheboygan (Wisconsin) | 658.11 mi (1,059.12 km) |
| Middle River to Shelby (North Carolina) | 396.82 mi (638.62 km) |
| Middle River to Shelbyville (Indiana) | 499.09 mi (803.20 km) |
| Middle River to Shelbyville (Kentucky) | 480.49 mi (773.27 km) |
| Middle River to Shelbyville (Tennessee) | 610.47 mi (982.46 km) |
