| Middle River to Sesena | 3,749.42 mi (6,034.11 km) |
| Middle River to Sestao | 3,693.38 mi (5,943.92 km) |
| Middle River to Sevilla | 3,721.06 mi (5,988.47 km) |
| Middle River to Sevilla La Nueva | 3,726.58 mi (5,997.36 km) |
| Middle River to Silla | 3,929.18 mi (6,323.41 km) |
| Middle River to Silleda | 3,463.51 mi (5,573.99 km) |
| Middle River to Sitges | 3,976.57 mi (6,399.67 km) |
| Middle River to Socuellamos | 3,816.62 mi (6,142.25 km) |
| Middle River to Soller | 4,064.31 mi (6,540.87 km) |
| Middle River to Solsona | 3,940.29 mi (6,341.28 km) |
| Middle River to Son Servera | 4,100.08 mi (6,598.44 km) |
| Middle River to Sonseca | 3,748.89 mi (6,033.26 km) |
| Middle River to Sopelana | 3,692.72 mi (5,942.86 km) |
| Middle River to Soria | 3,760.83 mi (6,052.47 km) |
| Middle River to Suances | 3,641.66 mi (5,860.68 km) |
