| Middle River to Sesimbra | 3,532.19 mi (5,684.51 km) |
| Middle River to Setubal | 3,540.22 mi (5,697.44 km) |
| Middle River to Sever do Vouga | 3,506.72 mi (5,643.52 km) |
| Middle River to Silves | 3,600.61 mi (5,794.62 km) |
| Middle River to Sines | 3,557.50 mi (5,725.25 km) |
| Middle River to Sintra | 3,508.14 mi (5,645.81 km) |
| Middle River to Sobrado de Paiva | 3,503.78 mi (5,638.79 km) |
| Middle River to Sobral de Monte Agraco | 3,513.88 mi (5,655.04 km) |
| Middle River to Soure | 3,511.69 mi (5,651.52 km) |
| Middle River to Tabua | 3,532.91 mi (5,685.67 km) |
| Middle River to Tavira | 3,642.06 mi (5,861.34 km) |
| Middle River to Tomar | 3,534.31 mi (5,687.93 km) |
| Middle River to Tondela | 3,526.15 mi (5,674.78 km) |
| Middle River to Torre de Moncorvo | 3,554.09 mi (5,719.76 km) |
| Middle River to Torres Novas | 3,532.19 mi (5,684.51 km) |
