| Middle River to Sacile | 4,299.93 mi (6,920.08 km) |
| Middle River to Sala Consilina | 4,632.07 mi (7,454.60 km) |
| Middle River to Salemi | 4,602.38 mi (7,406.81 km) |
| Middle River to Salerno | 4,584.47 mi (7,377.99 km) |
| Middle River to Salo | 4,228.92 mi (6,805.79 km) |
| Middle River to Salsomaggiore Terme | 4,230.86 mi (6,808.91 km) |
| Middle River to Saluzzo | 4,128.13 mi (6,643.58 km) |
| Middle River to Salzano | 4,298.34 mi (6,917.52 km) |
| Middle River to Samarate | 4,153.52 mi (6,684.44 km) |
| Middle River to San Benedetto del Tronto | 4,463.53 mi (7,183.35 km) |
| Middle River to San Biagio di Callalta | 4,304.37 mi (6,927.21 km) |
| Middle River to San Bonifacio | 4,267.44 mi (6,867.78 km) |
| Middle River to San Casciano in Val di Pesa | 4,321.78 mi (6,955.24 km) |
| Middle River to San Cataldo | 4,669.24 mi (7,514.41 km) |
| Middle River to San Cesareo | 4,456.60 mi (7,172.21 km) |
