| Middle Island to Storm Lake (Iowa) | 1,149.76 mi (1,850.36 km) |
| Middle Island to Storrs (Connecticut) | 73.21 mi (117.81 km) |
| Middle Island to Stoughton (Wisconsin) | 847.39 mi (1,363.74 km) |
| Middle Island to Stow (Ohio) | 442.73 mi (712.51 km) |
| Middle Island to Streamwood (Illinois) | 791.65 mi (1,274.03 km) |
| Middle Island to Streator (Illinois) | 827.24 mi (1,331.32 km) |
| Middle Island to Streetsboro (Ohio) | 438.13 mi (705.10 km) |
| Middle Island to Strongsville (Ohio) | 463.40 mi (745.76 km) |
| Middle Island to Stuart (Florida) | 1,033.08 mi (1,662.59 km) |
| Middle Island to Stuarts Draft (Virginia) | 380.39 mi (612.17 km) |
| Middle Island to Sturgis (Michigan) | 649.51 mi (1,045.29 km) |
| Middle Island to Suamico (Wisconsin) | 808.28 mi (1,300.81 km) |
| Middle Island to Sudley (Virginia) | 281.55 mi (453.11 km) |
| Middle Island to Suffern (New York) | 64.37 mi (103.59 km) |
| Middle Island to Suffolk (Virginia) | 351.22 mi (565.23 km) |
