| Middle Island to Seymour (Tennessee) | 679.85 mi (1,094.12 km) |
| Middle Island to Shady Hills (Florida) | 1,019.06 mi (1,640.01 km) |
| Middle Island to Shafter (California) | 2,510.36 mi (4,040.04 km) |
| Middle Island to Shaker Heights (Ohio) | 449.10 mi (722.75 km) |
| Middle Island to Shakopee (Minnesota) | 1,071.31 mi (1,724.10 km) |
| Middle Island to Sharon (Pennsylvania) | 394.18 mi (634.37 km) |
| Middle Island to Sharonville (Ohio) | 615.47 mi (990.51 km) |
| Middle Island to Shasta Lake (California) | 2,550.61 mi (4,104.80 km) |
| Middle Island to Shawnee (Kansas) | 1,162.09 mi (1,870.21 km) |
| Middle Island to Shawnee (Oklahoma) | 1,355.52 mi (2,181.49 km) |
| Middle Island to Sheboygan (Wisconsin) | 779.61 mi (1,254.66 km) |
| Middle Island to Shelby (North Carolina) | 606.23 mi (975.63 km) |
| Middle Island to Shelbyville (Indiana) | 682.95 mi (1,099.09 km) |
| Middle Island to Shelbyville (Kentucky) | 679.47 mi (1,093.50 km) |
| Middle Island to Shelbyville (Tennessee) | 821.21 mi (1,321.60 km) |
