| Middle Island to Scottsboro (Alabama) | 834.27 mi (1,342.63 km) |
| Middle Island to Scottsdale (Arizona) | 2,177.63 mi (3,504.56 km) |
| Middle Island to Scranton (Pennsylvania) | 145.96 mi (234.90 km) |
| Middle Island to Seabrook (Maryland) | 245.18 mi (394.58 km) |
| Middle Island to Seabrook (Texas) | 1,464.33 mi (2,356.62 km) |
| Middle Island to Seaford (New York) | 32.33 mi (52.03 km) |
| Middle Island to Seagoville (Texas) | 1,418.85 mi (2,283.42 km) |
| Middle Island to Seal Beach (California) | 2,499.70 mi (4,022.88 km) |
| Middle Island to Searcy (Arkansas) | 1,091.26 mi (1,756.22 km) |
| Middle Island to Seaside (California) | 2,615.68 mi (4,209.53 km) |
| Middle Island to SeaTac (Washington) | 2,445.32 mi (3,935.35 km) |
| Middle Island to Seattle (Washington) | 2,444.85 mi (3,934.60 km) |
| Middle Island to Sebastian (Florida) | 1,001.28 mi (1,611.40 km) |
| Middle Island to Sebring (Florida) | 1,045.02 mi (1,681.79 km) |
| Middle Island to Secaucus (New Jersey) | 59.02 mi (94.99 km) |
