| Middle Island to Sanford (Maine) | 208.14 mi (334.96 km) |
| Middle Island to Sanford (North Carolina) | 503.35 mi (810.06 km) |
| Middle Island to Sanger (California) | 2,497.14 mi (4,018.76 km) |
| Middle Island to Santa Ana (California) | 2,490.33 mi (4,007.80 km) |
| Middle Island to Santa Barbara (California) | 2,566.25 mi (4,129.98 km) |
| Middle Island to Santa Clara (California) | 2,604.53 mi (4,191.59 km) |
| Middle Island to Santa Clara (Oregon) | 2,526.59 mi (4,066.15 km) |
| Middle Island to Santa Clarita (California) | 2,502.89 mi (4,028.01 km) |
| Middle Island to Santa Cruz (California) | 2,617.61 mi (4,212.64 km) |
| Middle Island to Santa Fe (New Mexico) | 1,816.69 mi (2,923.68 km) |
| Middle Island to Santa Fe (Texas) | 1,475.94 mi (2,375.29 km) |
| Middle Island to Santa Fe Springs (California) | 2,494.08 mi (4,013.83 km) |
| Middle Island to Santa Maria (California) | 2,589.66 mi (4,167.66 km) |
| Middle Island to Santa Monica (California) | 2,513.28 mi (4,044.74 km) |
| Middle Island to Santa Paula (California) | 2,534.29 mi (4,078.55 km) |
