| Middle Island to Oswego (Illinois) | 799.97 mi (1,287.42 km) |
| Middle Island to Oswego (New York) | 254.07 mi (408.88 km) |
| Middle Island to Otsego (Minnesota) | 1,083.00 mi (1,742.93 km) |
| Middle Island to Ottawa (Illinois) | 826.07 mi (1,329.43 km) |
| Middle Island to Ottawa (Kansas) | 1,192.88 mi (1,919.76 km) |
| Middle Island to Ottumwa (Iowa) | 1,014.09 mi (1,632.03 km) |
| Middle Island to Overland (Missouri) | 935.68 mi (1,505.83 km) |
| Middle Island to Overland Park (Kansas) | 1,157.88 mi (1,863.43 km) |
| Middle Island to Overlea (Maryland) | 216.00 mi (347.62 km) |
| Middle Island to Oviedo (Florida) | 964.58 mi (1,552.35 km) |
| Middle Island to Owasso (Oklahoma) | 1,272.12 mi (2,047.28 km) |
| Middle Island to Owatonna (Minnesota) | 1,054.14 mi (1,696.48 km) |
| Middle Island to Owensboro (Kentucky) | 786.70 mi (1,266.08 km) |
| Middle Island to Owings Mills (Maryland) | 227.19 mi (365.63 km) |
| Middle Island to Owosso (Michigan) | 594.80 mi (957.24 km) |
