| Middle Island to Orangevale (California) | 2,534.90 mi (4,079.53 km) |
| Middle Island to Orchards (Washington) | 2,475.61 mi (3,984.11 km) |
| Middle Island to Orcutt (California) | 2,590.36 mi (4,168.79 km) |
| Middle Island to Oregon (Ohio) | 546.82 mi (880.02 km) |
| Middle Island to Oregon (Wisconsin) | 855.81 mi (1,377.29 km) |
| Middle Island to Oregon City (Oregon) | 2,483.02 mi (3,996.03 km) |
| Middle Island to Orem (Utah) | 2,016.87 mi (3,245.85 km) |
| Middle Island to Orinda (California) | 2,602.70 mi (4,188.64 km) |
| Middle Island to Orland Park (Illinois) | 775.54 mi (1,248.12 km) |
| Middle Island to Orlando (Florida) | 979.82 mi (1,576.87 km) |
| Middle Island to Ormond Beach (Florida) | 922.84 mi (1,485.17 km) |
| Middle Island to Oro Valley (Arizona) | 2,169.12 mi (3,490.86 km) |
| Middle Island to Oroville (California) | 2,534.29 mi (4,078.54 km) |
| Middle Island to Oshkosh (Wisconsin) | 823.65 mi (1,325.54 km) |
| Middle Island to Oskaloosa (Iowa) | 1,023.80 mi (1,647.65 km) |
