| Middle Island to Savignano sul Rubicone | 4,147.69 mi (6,675.06 km) |
| Middle Island to Savona | 3,970.20 mi (6,389.42 km) |
| Middle Island to Scafati | 4,359.19 mi (7,015.43 km) |
| Middle Island to Scalea | 4,450.66 mi (7,162.65 km) |
| Middle Island to Scandiano | 4,057.09 mi (6,529.25 km) |
| Middle Island to Scandicci | 4,106.77 mi (6,609.20 km) |
| Middle Island to Schio | 4,049.05 mi (6,516.32 km) |
| Middle Island to Sciacca | 4,414.68 mi (7,104.74 km) |
| Middle Island to Scicli | 4,516.18 mi (7,268.08 km) |
| Middle Island to Scordia | 4,503.43 mi (7,247.57 km) |
| Middle Island to Scorze | 4,085.63 mi (6,575.19 km) |
| Middle Island to Sedico | 4,067.29 mi (6,545.67 km) |
| Middle Island to Sedriano | 3,954.06 mi (6,363.44 km) |
| Middle Island to Segni | 4,258.76 mi (6,853.81 km) |
| Middle Island to Segrate | 3,968.00 mi (6,385.88 km) |
