| Middle Island to Santa Venerina | 4,501.69 mi (7,244.77 km) |
| Middle Island to Santeramo in Colle | 4,456.24 mi (7,171.63 km) |
| Middle Island to Santo Stefano di Magra | 4,037.64 mi (6,497.95 km) |
| Middle Island to Santo Stino di Livenza | 4,104.59 mi (6,605.69 km) |
| Middle Island to Sarezzo | 4,001.74 mi (6,440.18 km) |
| Middle Island to Sarno | 4,360.92 mi (7,018.22 km) |
| Middle Island to Saronno | 3,952.61 mi (6,361.11 km) |
| Middle Island to Sarzana | 4,041.20 mi (6,503.68 km) |
| Middle Island to Sassari | 4,091.89 mi (6,585.26 km) |
| Middle Island to Sasso Marconi | 4,087.78 mi (6,578.64 km) |
| Middle Island to Sassuolo | 4,062.66 mi (6,538.22 km) |
| Middle Island to Sava | 4,506.48 mi (7,252.48 km) |
| Middle Island to Saviano | 4,352.82 mi (7,005.19 km) |
| Middle Island to Savigliano | 3,922.23 mi (6,312.22 km) |
| Middle Island to Savignano sul Panaro | 4,075.64 mi (6,559.10 km) |
